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Products Details
Product Description
– DNMT-IN-1 is a potent DNMT inhibitor with an EC50 value of 3.2 µM. DNMT-IN-1 shows antiproliferative active[1].
Web ID
– HY-133030
Shipping
– Room temperature
Molecular Formula
– C15H9BrN2O6
References
– [1]Pechalrieu D, et al. Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells. Eur J Med Chem. 2020 Jan 15;186:111829.
CAS Number
– 2396691-28-2
Molecular Weight
– 393.15
SMILES
– Br[C@@]1([N+]([O-])=O)[C@@H](C2=C([N+]([O-])=O)C=CC=C2)OC3=CC=CC=C3C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA Methyltransferase
Isoform
– DNA Methyltransferase
Pathway
– Epigenetics
Product type
– Reference compound
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