Download Files:
Products Details
Product Description
– DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase[1].
Web ID
– HY-146227
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H24N4O3S
References
– [1]Lakshmi Manasa K, et al. Design and synthesis of β-carboline linked aryl sulfonyl piperazine derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability. Bioorg Chem. 2020 Aug;101:103983.
CAS Number
– 2459950-15-1
Molecular Weight
– 496.58
SMILES
– O=C(N1CCN(S(C2=CC=CC=C2)(=O)=O)CC1)C3=CC4=C(C(C5=CC=CC=C5)=N3)NC6=C4C=CC=C6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Topoisomerase
Pathway
– Apoptosis;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
