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DNA-PK-IN-4
SKU
HY-144037-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;PI3K/Akt/mTOR, DNA-PK
Products Details
Product Description
– DNA-PK-IN-4 is a potent inhibitor of DNA-PK. DNA-PK-IN-4 is a imidazolinone derivative compound. DNA-PK-IN-4 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021209055A1, compound 27)[1].
Web ID
– HY-144037
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H24N6O3
References
– [1]Yonggang Wei, et al. Imidazolinone derivatives and their applications in medicine. Patent WO2021209055A1.
CAS Number
– 2722645-10-3
Molecular Weight
– 396.44
SMILES
– O=C(NC)C1=CC=C(NC2=NC=C3N(C)C(N(C4CCOCC4)C3=N2)=O)C(C)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA-PK
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.