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Products Details
Product Description
– DNA-PK-IN-3 is a potent inhibitor of DNA-PK. DNA-PK-IN-3 synergistically enhances the effect of radiotherapy and chemotherapy and effectively inhibits tumor growth. DNA-PK-IN-3 also effectively reduces the damage to normal cells and reducing side effects. DNA-PK-IN-3 has the potential for the research of cancer disease (extracted from patent WO2021213460A1, compound 4)[1].
Web ID
– HY-144036
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H19N9O
References
– [1]Bin Liu, et al. Tricyclic kinase inhibitors. Patent WO2021213460A1.
CAS Number
– 2734846-19-4
Molecular Weight
– 389.41
SMILES
– CC1=CC2=NC=NN2C=C1NC3=NC=C4C(N(C5CCOCC5)C6=NC=CN64)=N3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA-PK
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
