Download Files:
Products Details
Product Description
– DNA-PK-IN-2 is a potent inhibitor of DNA-PK. DNA-dependent protein kinase (DNA-PK) is a DNA-PK enzyme complex composed of Ku70/Ku80 heterodimer and DNA-dependent protein kinase catalytic subunit (DNA-PKcs). DNA-PK-IN-2 has the potential for the research of cancer diseases (extracted from patent WO2021136462A1, compound 1)[1].
Web ID
– HY-142944
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H23N5O3
References
– [1]Yonggang Wei, et al. Furan derivatives and their applications in medicine. Patent WO2021136462A1.
CAS Number
– 2665720-22-7
Molecular Weight
– 381.43
SMILES
– O=C1N(C)C2=CN=C(NC3=CC4=C(C=C3C)OCC4)N=C2N1C5CCOCC5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA-PK
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
