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DNA-PK-IN-1
SKU
HY-142943-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;PI3K/Akt/mTOR, DNA-PK
Products Details
Product Description
– DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-dependent protein kinase (DNA-PK) is a DNA-PK enzyme complex composed of Ku70/Ku80 heterodimer and DNA-dependent protein kinase catalytic subunit (DNA-PKcs). DNA-PK-IN-1 has the potential for the research of cancer diseases (extracted from patent WO2021136463A1, compound 1)[1].
Web ID
– HY-142943
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H26N8O2
References
– [1]Yonggang Wei, et al. Purine derivatives and their use in medicine. Patent WO2021136463A1.
CAS Number
– 2663850-40-4
Molecular Weight
– 446.50
SMILES
– O=C1N(C)C2=CN=C(NC3=CN4C(C=C3C)=NC=N4)N=C2N1C5(CC6C7)CC7(O)CC(C6)C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA-PK
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.