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Products Details
Product Description
– DNA Gyrase-IN-5 (Compound 8I-w) is a potent DNA gyrase inhibitor with an IC50 of 0.10 μM. DNA Gyrase-IN-5 shows antibacterial activities against wild type and drug-resistant strains[1].
Web ID
– HY-147988
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C25H15BrClN5
References
– [1]Liu H, et al. Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase. Bioorg Chem. 2020 Jun;99:103807.
CAS Number
– 2417016-23-8
Molecular Weight
– 500.78
SMILES
– N#CC1=C(/N=C/C2=C(C3=CC=C(Br)C=C3)NC4=C2C=CC=C4)N(C5=CC=C(Cl)C=C5)N=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;DNA/RNA Synthesis
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
