Products Details

Product Description

– DNA Gyrase-IN-4 (compound 8p) is a potent DNA gyrase inhibitor, with an IC50 of 0.13 μM. DNA Gyrase-IN-4 shows excellent antibacterial activity against Staphylococcus aureus, Listeria monocytogenes, Salmonella and Escherichia coli, with MIC values of 0.05, 0.05, 0.05, and 8 μg/mL, respectively[1].

Web ID

– HY-147948

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C22H15Cl2NO4S

References

– [1]Liu H, et al. Novel coumarin-thiazolyl ester derivatives as potential DNA gyrase Inhibitors: Design, synthesis, and antibacterial activity. Bioorg Chem. 2020 Jul;100:103907.

CAS Number

– 2416400-32-1

Molecular Weight

– 460.33

SMILES

– O=C(C(C1=O)=CC2=C(O1)C=CC(Cl)=C2)OC(C3=CC=C(Cl)C=C3)C4=NC(C)=C(C)S4

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Bacterial;DNA/RNA Synthesis

Pathway

– Anti-infection;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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