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Products Details
Product Description
– DNA Gyrase-IN-1 (compound 42) is a potent and selective DNA gyrase inhibitor with an IC50 value of 2.6 µM. DNA Gyrase-IN-1 has high inhibitory activity against Mycobacterium tuberculosis (Mtb) with MIC of 0.49 µM. DNA Gyrase-IN-1 can be used for researching tuberculosis[1].
Web ID
– HY-147000
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C24H24FN7O6
References
– [1]Govender P, et al. Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity. J Med Chem. 2022;65(9):6903-6925.
Molecular Weight
– 525.49
SMILES
– C[C@@H]1N([C@@H](CN2C3=C(C4=C(C=C3CC5([C@]21[H])C(NC(NC5=O)=O)=O)C(OC[C@H]6NC(CC6)=O)=NO4)F)C)C#N
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;DNA/RNA Synthesis
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
