Download Files:
DNA gyrase B-IN-3
SKU
HY-149379-Get quote
Category Reference compound
Tags Anti-infection;Cell Cycle/DNA Damage, Bacterial;DNA/RNA Synthesis, Infection
Products Details
Product Description
– DNA gyrase B-IN-3 (Compound A) is a bacterial DNA gyrase B inhibitor (IC50: < 10 nM). DNA gyrase B-IN-3 has antibacterial activity against gram-positive strains[1].
Web ID
– HY-149379
Shipping
– Room temperature
Molecular Formula
– C14H9Cl2N3O4S
References
– [1]Sterle M, et al. Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens. ACS Omega. 2023 Jun 28;8(27):24387-24395.
CAS Number
– 2412834-56-9
Molecular Weight
– 386.21
SMILES
– OC(C1=CC(SC(NC(C2=C(Cl)C(Cl)=C(C)N2)=O)=N3)=C3C=C1O)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;DNA/RNA Synthesis
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.