Products Details

Product Description

– DNA gyrase B-IN-3 (Compound A) is a bacterial DNA gyrase B inhibitor (IC50: < 10 nM). DNA gyrase B-IN-3 has antibacterial activity against gram-positive strains[1].

Web ID

– HY-149379

Shipping

– Room temperature

Molecular Formula

– C14H9Cl2N3O4S

References

– [1]Sterle M, et al. Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens. ACS Omega. 2023 Jun 28;8(27):24387-24395.

CAS Number

– 2412834-56-9

Molecular Weight

– 386.21

SMILES

– OC(C1=CC(SC(NC(C2=C(Cl)C(Cl)=C(C)N2)=O)=N3)=C3C=C1O)=O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Bacterial;DNA/RNA Synthesis

Pathway

– Anti-infection;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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