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Products Details
Product Description
– DNA gyrase B-IN-1 (compound 13) is a potent DNA gyrase B inhibitor. DNA gyrase B-IN-1 shows inhibition of P. aeruginosa DNA gyrase B, with an IC50 of 2.2 μM. DNA gyrase B-IN-1 has good binding affinity and stability[1].
Web ID
– HY-147945
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C23H18ClF3N6O4S
References
– [1]Jogula S, et al. Design, synthesis and biological evaluation of novel Pseudomonas aeruginosa DNA gyrase B inhibitors. Bioorg Chem. 2020 Jul;100:103905.
Molecular Weight
– 566.94
SMILES
– NC(C(C(N)=O)=NS1)=C1C(N(C2=CC=C(N=C3C)C(O3)=C2)CC(NCC4=CC(C(F)(F)F)=CC(Cl)=C4)=O)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;DNA/RNA Synthesis
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
