Download Files:
DMU2139
$130 – $1,040
Products Details
Product Description
– DMU2139 is a potent and specific CYP1B1 inhibitor, with IC50s of 9 nM and 795 nM for CYP1B1 and CYP1A1, respectively.
Web ID
– HY-101285
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H15NO2
References
– [1]Horley NJ, et al. Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines. Eur J Med Chem. 2017 Mar 31;129:159-174.
CAS Number
– 1821143-80-9
Molecular Weight
– 289.33
Compound Purity
– 98.0
SMILES
– O=C(C1=CC=C2C=C(OC)C=CC2=C1)/C=C/C3=CC=CN=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 77.5 mg/mL (ultrasonic)|Ethanol : 5 mg/mL (ultrasonic)
Target
– Cytochrome P450
Isoform
– CYP1
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
