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DMH4
Products Details
Product Description
– DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM[1].
Web ID
– HY-108443
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H24N4O2
References
– [1]Hao J, et al. In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors. ACS Chem Biol. 2010 Feb 19;5(2):245-53.
CAS Number
– 515880-75-8
Molecular Weight
– 400.47
SMILES
– C12=C(C3=CC=CC=C3)C=NN1C=C(C4=CC=C(OCCN5CCOCC5)C=C4)C=N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– VEGFR
Isoform
– VEGFR2/KDR/Flk-1
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.