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DMH2
$396 – $634
Products Details
Product Description
– DMH2 is a potent BMP receptor antagonist. DMH2 downregulates the expression of Id1 and Id3 proteins, and inhibits the proliferation and induces cell death of lung cancer cell lines[1].
Web ID
– HY-110245
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H25N5O2
References
– [1]Langenfeld J E, Langenfeld E. Src inhibition enhances BMP receptor antagonists downregulation of Id1 and growth suppression of lung cancer cells with a K-Ras mutation. 2013:5263.|[2]Tsugawa D, Oya Y, Masuzaki R, et al. Specific activin receptor-like kinase 3 inhibitors enhance liver regeneration. J Pharmacol Exp Ther. 2014;351(3):549-558.
CAS Number
– 1206711-14-9
Molecular Weight
– 451.52
SMILES
– C1(C2=C3N=CC(C4=CC=C(OCCN5CCOCC5)C=C4)=CN3N=C2)=C6C=CC=CC6=NC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
