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Products Details
Product Description
– DMEA-PNU-159682 (molecule D12) dichloroacetate is an ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].
Web ID
– HY-126665A
Shipping
– Room temperature
Molecular Formula
– C41H49Cl4N3O18
References
– [1]Chen Jingkang, et al. Disubstituted maleic amide class connexon for antibody-drug conjugate and its preparation method and application. CN108101825A.|[2]John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1
CAS Number
– 1799421-49-0
Molecular Weight
– 1013.65
SMILES
– OC(C(Cl)Cl)=O.C[C@H]1[C@]2([H])[C@](N3[C@]([C@H](OCC3)OC)([H])O2)([H])C[C@](O1)([H])O[C@@H]4C5=C(C[C@](C(COC(N(C)CCNC)=O)=O)(O)C4)C(O)=C6C(C(C7=C(OC)C=CC=C7C6=O)=O)=C5O.OC(C(Cl)Cl)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
