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Products Details
Product Description
– DL-3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) disodium is a disodium salt compound of HMG-CoA, is a intermediate of terpenes and ketone bodies. DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium also involves in ester metabolism in vivo, as a precursor for cholesterol synthesis, and regulates cholesterol synthesis by coupling LDL receptor[1][2].
Web ID
– HY-114294A
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C27H44N7Na2O20P3S
References
– [1]Millán Núñez-Cortés J, et al. Fármacos hipolipemiantes y PCSK9 [Lipid-lowering drugs and PCSK9]. Clin Investig Arterioscler. 2016 May;28 Suppl 2:9-13. Spanish. |[2]Wang Wei, er al. The Key Enzyme of Cholesterol Synthesis Pathway:HMG CoA Reductase and Disease. PROGRESS IN PHYSIOLOGICAL SCIENCES. 1999. (01):7-11.
CAS Number
– 103476-21-7
Molecular Weight
– 957.64
SMILES
– O[C@H]1[C@](O[C@@H]([C@H]1OP(O)(O)=O)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CC(C)(O)CC(O)=O)=O)=O)=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2.[Na].[Na]
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Biochemical Assay Reagents
Pathway
– Others
Product type
– Biochemical Assay Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
