![](https://immunomart.com/wp-content/uploads/2024/03/HY-149348.gif)
Download Files:
DiPT-4
SKU
HY-149348-Get quote
Category Reference compound
Tags Apoptosis;Cell Cycle/DNA Damage;Epigenetics, Apoptosis;PARP;Topoisomerase, Cancer
Products Details
Product Description
– DiPT-4 is a dual TOP1/PARP1 inhibitor that induces massive DNA double-strand breaks (DSBs), cell cycle arrest, and apoptosis in cancer cells. DiPT-4 has the potential to overcome cancer drug resistance[1].
Web ID
– HY-149348
Shipping
– Room temperature
Molecular Formula
– C32H22FN5O4S
References
– [1]Guha Majumdar A, et al. Design, synthesis and development of a dual inhibitor of Topoisomerase 1 and poly (ADP-ribose) polymerase 1 for efficient killing of cancer cells. Eur J Med Chem. 2023 Oct 5;258:115598.
Molecular Weight
– 591.61
SMILES
– O=C1N(CC2=NN=C(SCCN3C(C4=CC=CC5=CC=CC(C3=O)=C45)=O)O2)N=C(CC6=CC=C(F)C=C6)C7=C1C=CC=C7
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;PARP;Topoisomerase
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.