Diphenidol (hydrochloride)

$60$66

Products Details

Product Description

– Diphenidol hydrochloride (Difenidol hydrochloride) is a non-selective muscarinic M1-M4 receptor antagonist, has anti-arrhythmic activity. Diphenidol hydrochloride is also a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells[1][2].

Web ID

– HY-A0082

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C21H28ClNO

References

– [1]Leung YM, et al. Inhibition of voltage-gated K+ channels and Ca2+ channels by diphenidol. Pharmacol Rep. 2012;64(3):739-44.|[2]Leung YM, et al. Diphenidol inhibited sodium currents and produced spinal anesthesia. Neuropharmacology. 2010 Jun;58(7):1147-52.|[3]Andersson M, et al. Muscarinic receptor subtypes involved in urothelium-derived relaxatory effects in the inflamed rat urinary bladder. Auton Neurosci. 2012 Sep 25;170(1-2):5-11.

CAS Number

– 3254-89-5

Molecular Weight

– 345.91

Compound Purity

– 99.95

SMILES

– OC(C1=CC=CC=C1)(C2=CC=CC=C2)CCCN3CCCCC3.[H]Cl

Clinical Information

– Launched

Research Area

– Neurological Disease

Solubility

– DMSO : ≥ 46 mg/mL|H2O : 16.67 mg/mL (ultrasonic)

Target

– mAChR;Sodium Channel

Isoform

– mAChR1;mAChR2;mAChR3;mAChR4

Pathway

– GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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