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Diphenidol (hydrochloride)
$60 – $66
Products Details
Product Description
– Diphenidol hydrochloride (Difenidol hydrochloride) is a non-selective muscarinic M1-M4 receptor antagonist, has anti-arrhythmic activity. Diphenidol hydrochloride is also a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells[1][2].
Web ID
– HY-A0082
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H28ClNO
References
– [1]Leung YM, et al. Inhibition of voltage-gated K+ channels and Ca2+ channels by diphenidol. Pharmacol Rep. 2012;64(3):739-44.|[2]Leung YM, et al. Diphenidol inhibited sodium currents and produced spinal anesthesia. Neuropharmacology. 2010 Jun;58(7):1147-52.|[3]Andersson M, et al. Muscarinic receptor subtypes involved in urothelium-derived relaxatory effects in the inflamed rat urinary bladder. Auton Neurosci. 2012 Sep 25;170(1-2):5-11.
CAS Number
– 3254-89-5
Molecular Weight
– 345.91
Compound Purity
– 99.95
SMILES
– OC(C1=CC=CC=C1)(C2=CC=CC=C2)CCCN3CCCCC3.[H]Cl
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 46 mg/mL|H2O : 16.67 mg/mL (ultrasonic)
Target
– mAChR;Sodium Channel
Isoform
– mAChR1;mAChR2;mAChR3;mAChR4
Pathway
– GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
