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Diphenhydramine-d6 (hydrochloride)
$80 – $190
Products Details
Product Description
– Diphenhydramine-d6 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].
Web ID
– HY-B0303AS
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Molecular Formula
– C17H16D6ClNO
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Simons FE. H1-receptor antagonists. Comparative tolerability and safety. Drug Saf. 1994;10(5):350-380.
CAS Number
– 1189986-72-8
Molecular Weight
– 297.85
Compound Purity
– 98.83
SMILES
– [2H]C([2H])([2H])N(C([2H])([2H])[2H])CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;Histamine Receptor;Isotope-Labeled Compounds
Isoform
– H1 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.