Products Details

Product Description

– Dinoprost-d4 is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour[1][2].

Web ID

– HY-12956S

Shipping

– Room temperature

Molecular Formula

– C20H30D4O5

References

– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Hagen Thieme, et al. Endothelin antagonism: effects of FP receptor agonists prostaglandin F2alpha and fluprostenol on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2006 Mar;47(3):938-45.|[3]Xin Wen, et al. Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy. Front Physiol. 2020 Sep 11;11:868.

CAS Number

– 34210-11-2

Molecular Weight

– 358.51

SMILES

– OC(CC([2H])([2H])C([2H])([2H])/C=CC[C@@H]([C@H](C1)O)[C@H]([C@@H]1O)/C=C/[C@@H](O)CCCCC)=O

Clinical Information

– No Development Reported

Research Area

– Endocrinology

Solubility

– 10 mM in DMSO

Target

– Apoptosis;Autophagy;Endogenous Metabolite;Isotope-Labeled Compounds;Prostaglandin Receptor

Isoform

– FP

Pathway

– Apoptosis;Autophagy;GPCR/G Protein;Metabolic Enzyme/Protease;Others

Product type

– Isotope-Labeled Compounds

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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