Dilmapimod

$50$450

Products Details

Product Description

– Dilmapimod (SB-681323) is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease.

Web ID

– HY-10404

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C23H19F3N4O3

References

– [1]Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50(1):94-100.

CAS Number

– 444606-18-2

Molecular Weight

– 456.42

Compound Purity

– 99.56

SMILES

– O=C1C=CC2=C(C3=CC=C(F)C=C3C)N=C(NC(CO)CO)N=C2N1C4=C(F)C=CC=C4F

Clinical Information

– Phase 2

Research Area

– Inflammation/Immunology; Cancer

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– Autophagy;p38 MAPK

Pathway

– Autophagy;MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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