Products Details

Product Description

– DHQZ 36 is a potent inhibitor of retrograde trafficking. DHQZ 36 inhibits Leishmania amazonensis infection in macrophages with an EC50 of 13.63 μM. DHQZ 36 has potent anti-parasite activity[1].

Web ID

– HY-123601

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C21H18F2N2OS

References

– [1]Craig E, et al. Structurally optimized analogs of the retrograde trafficking inhibitor Retro-2cycl limit Leishmania infections. PLoS Negl Trop Dis. 2017 May 15;11(5):e0005556.

CAS Number

– 1542098-94-1

Molecular Weight

– 384.44

SMILES

– O=C1N(CC2=CC=C(F)C=C2)C(C3=CC=C(CC)S3)NC4=C1C=C(F)C=C4

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Parasite

Isoform

– Leishmania

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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