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Products Details
Product Description
– DHODH-IN-18 is a human DHODH inhibitor (IC50 = 0.2 nM).
Web ID
– HY-139889
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H16ClF5N6O4
References
– [1]Sabnis RW. Heterocyclic Compounds as Dihydroorotate Dehydrogenase Inhibitors for Treating Acute Myelogenous Leukemia (AML). ACS Med Chem Lett. 2021 Oct 20;12(11):1641-1642.
CAS Number
– 2685799-97-5
Molecular Weight
– 546.83
SMILES
– ClC1=CC=CC(F)=C1OC2=NN=CC3=C(F)C(N4N=C(CO)N(CC)C4=O)=NC(O[C@H](C(F)(F)F)C)=C32
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Dihydroorotate Dehydrogenase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
