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DHODH-IN-13
$315
Only 1000 item(s) left in stock.
Products Details
Product Description
– DHODH-IN-13 (Compound 7a) is a hydroxyfurazan analog of A771726. DHODH-IN-13 is a dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 4.3 μM for rat liver DHODH. DHODH-IN-13 can be used for rheumatoid arthritis[1].
Web ID
– HY-135677
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C10H6F3N3O3
References
– [1]Lolli ML, et al. New inhibitors of dihydroorotate dehydrogenase (DHODH) based on the 4-hydroxy-1,2,5-oxadiazol-3-yl (hydroxyfurazanyl) scaffold. Eur J Med Chem. 2012 Mar;49:102-9.
CAS Number
– 1364791-86-5
Molecular Weight
– 273.17
SMILES
– O=C(C1=NONC1=O)NC2=CC=C(C(F)(F)F)C=C2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Dihydroorotate Dehydrogenase;DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
