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DHODH-IN-12
SKU
HY-135676-1mg
Category Reference compound
Tags Cell Cycle/DNA Damage;Metabolic Enzyme/Protease, Dihydroorotate Dehydrogenase;DNA/RNA Synthesis, Inflammation/Immunology
$315
Only 1000 item(s) left in stock.
Products Details
Product Description
– DHODH-IN-12 (Compound 12b) is a Leflunomide derivative and a weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07[1].
Web ID
– HY-135676
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C10H9N3O2
References
– [1]Giorgis M, et al. 1,2,5-Oxadiazole analogues of leflunomide and related compounds. Eur J Med Chem. 2011 Jan;46(1):383-92.
CAS Number
– 1263303-93-0
Molecular Weight
– 203.20
SMILES
– O=C(NC1=CC=C(C)C=C1)/C(C#N)=N/O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Dihydroorotate Dehydrogenase;DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.