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Products Details
Product Description
– DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor for MtDHFR (dihydrofolate reductase from M. tuberculosis), with an IC50 of 7 μM. DHFR-IN-2 can be used for tuberculosis (TB) research[1].
Web ID
– HY-147661
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C14H13NO2
References
– [1]Kronenberger T,et al. Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors. Bioorg Med Chem. 2020 Aug 1;28(15):115600.
CAS Number
– 331942-46-2
Molecular Weight
– 227.26
SMILES
– O=C(C1=CC(CNC2=CC=CC=C2)=CC=C1)O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antifolate
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
