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Products Details
Product Description
– DHFR-IN-10 (compound 4c) is a potent DHFR inhibitor, with an IC50 of 4.21 μM for M. tuberculosis DHFR enzyme. DHFR-IN-10 exhibits potent antituberculosis efficiency[1].
Web ID
– HY-156412
Shipping
– Room temperature
Molecular Formula
– C20H14BrN3S3
References
– [1]Dawood DH, et, al. New Thiophenyl-pyrazolyl-thiazole Hybrids as DHFR Inhibitors: Design, Synthesis, Antimicrobial Evaluation, Molecular Modeling, and Biodistribution Studies. ACS Omega. 2023 Oct 13;8(42):39250-39268.
CAS Number
– 929484-47-9
Molecular Weight
– 472.44
SMILES
– BrC1=CC=C(C2=CSC(N3N=C(C4=CC=CS4)CC3C5=CC=CS5)=N2)C=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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