DGY-06-116

SKU HY-136605-10 mg Category Tags , ,

$120$900

Products Details

Product Description

– DGY-06-116 is an irreversible covalent, selective Src inhibitor with an IC50 of 3nM. DGY-06-116 inhibits FGFR1 with an IC50 of 8340 nM[1].

Web ID

– HY-136605

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C32H33ClN8O2

References

– [1]Guangyan Du, et al. Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine. J Med Chem. 2020 Feb 27;63(4):1624-1641.|[2]Deepak Gurbani, et al. Structure and Characterization of a Covalent Inhibitor of Src Kinase. Front Mol Biosci. 2020 May 19;7:81.

CAS Number

– 2556836-50-9

Molecular Weight

– 597.11

Compound Purity

– 99.38

SMILES

– O=C(NC1=C(Cl)C=CC=C1C)C(C=N2)=C(NC3=C(NC(C=C)=O)C=CC=C3)N=C2NC4=CC=C(N5CCN(C)CC5)C=C4

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– Src

Pathway

– Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

My Cart
Close Wishlist
Close Recently Viewed
Categories

Please fill out this form to request the file. We will send it to your Email address shortly. Thanks.

Please enable JavaScript in your browser to complete this form.

=

Please fill out this form to request the pricing.
We will send it to your email address shortly.
Thanks.

Please enable JavaScript in your browser to complete this form.

=