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Dextran sulfate sodium salt (MW5000)
SKU
HY-116282-10 g
Category Biochemical Assay Reagents
Tags Anti-infection;Apoptosis, Apoptosis;HIV, Infection; Inflammation/Immunology
$30 – $50
Products Details
Product Description
– Dextran sulfate sodium salt (MW5000) is a polymer of anhydroglucose with the molecular weight of 5000. Dextran sulfate sodium salt can be used to induce colitis. Dextran sulfate sodium salt also can inhibit the replication of the human immunodeficiency virus (HIV) by preventing the adsorption of the virus into host cells[1][2][3].
Web ID
– HY-116282
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– N/A
References
– [1]Regmi S, et, al. Enhanced viability and function of mesenchymal stromal cell spheroids is mediated via autophagy induction. Autophagy. 2021 Oct;17(10):2991-3010.|[2]Baba M, et al. Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro. Proc Natl Acad Sci U S A. 1988 Aug;85(16):6132-6.|[3]Araki Y, et, al. Dextran sulfate sodium administered orally is depolymerized in the stomach and induces cell cycle arrest plus apoptosis in the colon in early mouse colitis. Oncol Rep. 2012 Nov;28(5):1597-605.
CAS Number
– 9011-18-1
Molecular Weight
– 5000(Average)
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– H2O : 100 mg/mL (ultrasonic)
Target
– Apoptosis;HIV
Pathway
– Anti-infection;Apoptosis
Product type
– Biochemical Assay Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.