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Dexrazoxane (hydrochloride)
$38 – $156
Products Details
Product Description
– Dexrazoxane hydrochloride (ICRF-187 hydrochloride) is a cardioprotective agent.
Web ID
– HY-76201
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C11H18Cl2N4O4
Citations
– Environ Toxicol Pharmacol. 2023 Sep 7;104261.|Nat Med. 2016 May;22(5):547-56. |Adv Sci (Weinh). 2023 Mar 26;e2206007.|Biomed Pharmacother. 2022 Jun 17;153:113280.|Free Radic Biol Med. 2020 Nov 20;160:303-318.|Nano Res. 2023 Apr 18.|Phytomedicine. 2023 Jun 10, 154922.
References
– [1]Hasinoff BB. The use of dexrazoxane for the prevention of anthracycline extravasation injury. Expert Opin Investig Drugs. 2008 Feb;17(2):217-23.|[2]Jones RL. Utility of dexrazoxane for the reduction of anthracycline-induced cardiotoxicity. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1311-7.|[3]Lipshultz SE, Scully RE, Lipsitz SR et al. Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial. Lancet Oncol. 2010 Oct;11(10):950-61.
CAS Number
– 149003-01-0
Molecular Weight
– 341.19
Compound Purity
– 99.32
SMILES
– C[C@H](N(C1)CC(NC1=O)=O)CN(C2)CC(NC2=O)=O.[H]Cl.[H]Cl
Clinical Information
– Launched
Research Area
– Cardiovascular Disease; Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : 20 mg/mL (ultrasonic)
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
