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Dexrazoxane
$50 – $130
Products Details
Product Description
– Dexrazoxane (ICRF-187) is a cardioprotective agent.
Web ID
– HY-B0581
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C11H16N4O4
Citations
– Adv Sci (Weinh). 2023 Mar 26;e2206007.|Biomed Pharmacother. 2022 Jun 17;153:113280.|Free Radic Biol Med. 2020 Nov 20;160:303-318.|Nano Res. 2023 Apr 18.|Phytomedicine. 2023 Jun 10, 154922.|Environ Toxicol Pharmacol. 2023 Sep 7;104261.|Nat Med. 2016 May;22(5):547-56.
References
– [1]Jones, R.L., Utility of dexrazoxane for the reduction of anthracycline-induced cardiotoxicity. Expert Rev Cardiovasc Ther, 2008. 6(10): p. 1311-7.|[2]Loyevsky, M., et al., Plasmodium falciparum and Plasmodium yoelii: effect of the iron chelation prodrug dexrazoxane on in vitro cultures. Exp Parasitol, 1999. 91(2): p. 105-14.
CAS Number
– 24584-09-6
Molecular Weight
– 268.27
Compound Purity
– 99.76
SMILES
– C[C@H](N(C1)CC(NC1=O)=O)CN(C2)CC(NC2=O)=O
Clinical Information
– Launched
Research Area
– Cardiovascular Disease; Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic)
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
