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Products Details
Product Description
– Dexamethasone (Hexadecadrol) (GMP) is Dexamethasone (HY-14648) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Dexamethasone is an agonist of glucocorticoid receptor[1][2][3][4].
Web ID
– HY-14648G
Shipping
– Room temperature
Molecular Formula
– C22H29FO5
References
– [1]Tenenbaum HC, Heersche JN. Dexamethasone stimulates osteogenesis in chick periosteum in vitro. Endocrinology. 1985 Nov;117(5):2211-7.|[2]Rickard DJ, et al. Induction of rapid osteoblast differentiation in rat bone marrow stromal cell cultures by dexamethasone and BMP-2. Dev Biol. 1994 Jan;161(1):218-28.|[3]Alliot-Licht B, et al. Dexamethasone stimulates differentiation of odontoblast-like cells in human dental pulp cultures. Cell Tissue Res. 2005 Sep;321(3):391-400.|[4]Grigoriadis AE, et al. Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone. J Cell Biol. 1988 Jun;106(6):2139-51.
CAS Number
– 50-02-2
Molecular Weight
– 392.46
SMILES
– O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H](C)[C@@]4(C(CO)=O)O)=C1
Clinical Information
– Phase 4
Research Area
– Cancer; Infection; Endocrinology; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Glucocorticoid Receptor
Pathway
– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
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