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Products Details
Product Description
– Desmethyl Vc-seco-DUBA consists a cleavable ADC linker (Desmethyl Vc-seco) and a DNA alkylating agent (DUBA). Desmethyl Vc-seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-131085
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C64H73ClN12O17
References
– [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Molecular Weight
– 1317.79
SMILES
– O=C(N(CCN(CCOCCO)C(OC1=CC2=C(C3=CC=CC=C31)[C@H](CCl)CN2C(C4=CN5C=C(NC(C6=CC=C(O)C=C6)=O)C=CC5=N4)=O)=O)C)OCC7=CC=C(C=C7)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCCOCCN8C(C=CC8=O)=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Isoform
– Duocarmycins
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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