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Products Details
Product Description
– Desethylamiodarone (N-Deethylamiodarone) is the major metabolite of antiarrhythmic compound Amiodarone (HY-14187). Desethylamiodarone has antiarrhythmic activity. Desethylamiodaron also induces cancer cell apoptosis[1][2].
Web ID
– HY-122423
Shipping
– Room temperature
Molecular Formula
– C23H25I2NO3
References
– [1]Kannan R, et al. Amiodarone toxicity. II. Desethylamiodarone-induced phospholipidosis and ultrastructural changes during repeated administration in rats. Fundam Appl Toxicol. 1991 Jan;16(1):103-9.|[2]Bognar Z, et al. Desethylamiodarone-A metabolite of amiodarone-Induces apoptosis on T24 human bladder cancer cells via multiple pathways. PLoS One. 2017 Dec 8;12(12):e0189470.
CAS Number
– 83409-32-9
Molecular Weight
– 617.26
SMILES
– O=C(C1=CC(I)=C(C(I)=C1)OCCNCC)C2=C(OC3=CC=CC=C23)CCCC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Drug Metabolite
Pathway
– Apoptosis;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
