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Deoxycorticosterone acetate
$60 – $66
Products Details
Product Description
– Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria[1][2].
Web ID
– HY-B1472
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C23H32O4
References
– [1]Lu NZ, et al. International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacol Rev. 2006 Dec;58(4):782-97. |[2]Lother A, et al. Deoxycorticosterone Acetate/Salt-Induced Cardiac But Not Renal Injury Is Mediated By Endothelial Mineralocorticoid Receptors Independently From Blood Pressure. Hypertension. 2016 Jan;67(1):130-8.Â
CAS Number
– 56-47-3
Molecular Weight
– 372.50
Compound Purity
– 99.57
SMILES
– C[C@@]12[C@@H](C(COC(C)=O)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC2)=O
Clinical Information
– Launched
Research Area
– Endocrinology
Solubility
– DMSO : 41.67 mg/mL (ultrasonic;warming;heat to 80°C)|H2O : 1 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– Endogenous Metabolite;Mineralocorticoid Receptor
Isoform
– Human Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
