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DENV-IN-5
SKU
HY-143274-1mg
Category Reference compound
Tags Anti-infection;Cell Cycle/DNA Damage, DNA/RNA Synthesis;Flavivirus;HIV, Infection
$862
Only 1000 item(s) left in stock.
Products Details
Product Description
– DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM[1].
Web ID
– HY-143274
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C23H25ClF2N4OS
References
– [1]Rui RM, et al. C6-structural optimizations of 2-aryl-1H-pyrazole-S-DABOs: From anti-HIV to anti-DENV activity. Bioorg Chem. 2022 Feb;119:105494.
CAS Number
– 2375781-06-7
Molecular Weight
– 478.99
SMILES
– CCC1=C(N=C(NC1=O)SCC2=NNC(C3=CC(F)=C(C=C3)F)=C2Cl)CC4CCCCC4
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis;Flavivirus;HIV
Isoform
– HIV-1
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.