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Products Details
Product Description
– DENV-IN-4 is a potent DENV inhibitor (DENV EC50=4.79 μM, Vero CC50>100 μM, SI>20.9). DENV-IN-4 can inhibit the expression level of DENV2 with concentration-dependence and reduce RNA-dependent RNA polymerase (RdRp) enzymatic activity. DENV-IN-4 has antiviral effect[1].
Web ID
– HY-115929
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C28H32N4O4Si
References
– [1]Qian W, et al. Design, synthesis, discovery and SAR of the fused tricyclic derivatives of indoline and imidazolidinone against DENV replication and infection [published online ahead of print, 2022 Jan 24]. Bioorg Chem. 2022;120:105639.
CAS Number
– 2762302-75-8
Molecular Weight
– 516.66
SMILES
– O=C1[C@@](CC2=CC=CC=C23)([H])N3[C@](C4=CC=C(C=C4)O[Si](C)(C)C(C)(C)C)([H])N1NC5=CC=C(C=C5)[N+]([O-])=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
