Demycarosyl-3D-β-D-digitoxosylmithramycin SK

SKU HY-N11669-Get quote Category Tags , ,

Products Details

Product Description

– Demycarosyl-3D-β-D-digitoxosylmithramycin SK is a Mithramycin analog with good anti-tumor activity, which can prevent the proliferation and growth of tumor cells by binding and inhibiting DNA-binding proteins[1].

Web ID

– HY-N11669

Shipping

– Room temperature

Molecular Formula

– C50H72O23

References

– [1]Núñez, et al. A Novel Mithramycin Analogue with High Antitumor Activity and Less Toxicity Generated by Combinatorial Biosynthesis. Journal of Medicinal Chemistry, 55(12), 5813-5825.

CAS Number

– 1262896-48-9

Molecular Weight

– 1041.09

SMILES

– O=C([C@H]1O[C@H](O[C@@H]2C)C[C@H]([C@@H]2O)O[C@H](O[C@@H]3C)C[C@H]([C@H]3O)O[C@H](O[C@@H]4C)C[C@@H]([C@@H]4O)O)C(C(C[C@@]1([H])[C@H](OC)[C@@H](O)C(C)=O)=CC5=CC(O[C@H](O[C@@H]6C)C[C@H]([C@@H]6O)O[C@H](O[C@@H]7C)C[C@H]([C@@H]7O)O)=C8C)=C(C5=C8O)O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– DNA/RNA Synthesis

Pathway

– Cell Cycle/DNA Damage

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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