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Products Details
Product Description
– Demethylasterriquinone B1 is a selective insulin receptor activator. Demethylasterriquinone B1 stimulates tyrosine phosphorylation of the IR β subunit, and the activation of PIK3 and AKT[1].
Web ID
– HY-107586
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C32H30N2O4
References
– [1]Li M, et al. Small molecule insulin receptor activators potentiate insulin action in insulin-resistant cells. Diabetes. 2001;50(10):2323-2328.
CAS Number
– 78860-34-1
Molecular Weight
– 506.59
SMILES
– C=CC(C)(C1=C(C(C(C(O)=C2C3=CNC4=C3C=CC=C4C/C=C(C)/C)=O)=C(O)C2=O)C5=C(C=CC=C5)N1)C
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– Akt;Insulin Receptor
Pathway
– PI3K/Akt/mTOR;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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