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Delta-12-Prostaglandin J2
$94
Only 1000 item(s) left in stock.
Products Details
Product Description
– Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation[1][2].
Web ID
– HY-113505
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H30O4
References
– [1]Kim BE, et al. Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by Delta12-prostaglandin J2. Exp Mol Med. 2004;36(5):444-453.
CAS Number
– 87893-54-7
Molecular Weight
– 334.45
SMILES
– CCCCC[C@H](O)C/C=C1[C@H](C=CC1=O)C/C=CCCCC(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Endogenous Metabolite
Isoform
– Human Endogenous Metabolite
Pathway
– Apoptosis;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
