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Product Description
– Delparantag (PMX-60056) is a salicylamide derivative and an effective unfractionated heparin (UFH) and low molecular weight heparin (LMWH) reversing agent. Delparantag shows ability to neutralize the anticoagulation and bleeding effects of UFH and LMWH[1][2].
Web ID
– HY-105240
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C56H79N13O12
References
– [1]Mahan CE. A 1-year drug utilization evaluation of protamine in hospitalized patients to identify possible future roles of heparin and low molecular weight heparin reversal agents. J Thromb Thrombolysis. 2014 Apr;37(3):271-8.|[2]Kuziej J, et al. In vivo neutralization of unfractionated heparin and low-molecular-weight heparin by a novel salicylamide derivative. Clin Appl Thromb Hemost. 2010 Aug;16(4):377-86.
CAS Number
– 872454-31-4
Molecular Weight
– 1126.31
SMILES
– O=C(C(C=C1NC([C@H](CCCCN)NC(C(C=C2NC([C@@H](N)CCCCN)=O)=C(C=C2)OC)=O)=O)=C(C=C1)OC)N[C@@H](CCCCN)C(NC(C=C3)=CC(C(N[C@@H](CCCCN)C(NC(C=C4)=CC(C(N)=O)=C4OC)=O)=O)=C3OC)=O
Clinical Information
– Phase 2
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Factor Xa
Pathway
– Metabolic Enzyme/Protease
Product type
– Peptides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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