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Products Details
Product Description
– DDO-8926 is a potent and selective BET inhibitor that can significantly reduce mechanical hypersensitivity by inhibiting the expression of pro-inflammatory cytokines and reducing excitability for neuropathic pain research[1].
Web ID
– HY-149863
Shipping
– Room temperature
Molecular Formula
– C20H21FN6O2S
References
– [1]Xuetao Chen, et al. Discovery of 1H-Imidazo[4,5-b]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain. J Med Chem. 2023 Jul 13;66(13):8725-8744.Â
Molecular Weight
– 428.48
SMILES
– CC1=NN(C(C)=C1C2=C(C(C3=C4NC=NC4=NC=C3)=CC(NS(CC)(=O)=O)=C2)F)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
