Download Files:
DCN1-UBC12-IN-3
SKU
HY-142692-Get quote
Category Reference compound
Tags Cardiovascular Disease, E1/E2/E3 Enzyme, Metabolic Enzyme/Protease
Products Details
Product Description
– DCN1-UBC12-IN-3 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.25 nM. Anticardiac fibrotic effect[1].
Web ID
– HY-142692
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C30H30N8O3S2
References
– [1]He ZX, et al. Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65(1):163-190.
CAS Number
– 2374827-45-7
Molecular Weight
– 614.74
SMILES
– N#CC1=C(C2=CC(OC)=C(OC)C(OC)=C2)N=C(SCC3=CC=C4C=CC=CC4=C3)N=C1SC5=NN=NN5CCN(C)C
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– E1/E2/E3 Enzyme
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.