Products Details

Product Description

– DCN1-UBC12-IN-3 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.25 nM. Anticardiac fibrotic effect[1].

Web ID

– HY-142692

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C30H30N8O3S2

References

– [1]He ZX, et al. Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65(1):163-190.

CAS Number

– 2374827-45-7

Molecular Weight

– 614.74

SMILES

– N#CC1=C(C2=CC(OC)=C(OC)C(OC)=C2)N=C(SCC3=CC=C4C=CC=CC4=C3)N=C1SC5=NN=NN5CCN(C)C

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– E1/E2/E3 Enzyme

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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