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Products Details
Product Description
– DCN1-UBC12-IN-2 is a potent and specific DCN1-UBC12 inhibitor (IC50=9.55 nM). DCN1-UBC12-IN-2 could specifically target DCN1-UBC12 interaction and relieve Ang II-induced cardiac fibroblast activation[1].
Web ID
– HY-142694
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H20ClN7O3S2
References
– [1]He ZX, et al. Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects. J Med Chem. 2022;65(1):163-190.
CAS Number
– 2374827-47-9
Molecular Weight
– 542.03
SMILES
– N#CC1=C(C2=CC(OC)=C(OC)C(OC)=C2)N=C(SCC3=CC=C(Cl)C=C3)N=C1SC4=NN=NN4C
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– E1/E2/E3 Enzyme
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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