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Products Details
Product Description
– DC07090 dihydrochloride is a low toxicity, potent, reversible and competitive non-peptidyl human enterovirus 71 3C protease inhibitor with an IC50 and a Ki value for 21.72 μM and 23.29 μM. DC07090 dihydrochloride could also inhibit coxsackievirus A16 (CVA16) replication with an EC50 value of 27.76 μM[1].
Web ID
– HY-123517
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C18H16Cl2N4O
References
– [1]Ma GH, et al. Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening. Eur J Med Chem. 2016 Nov 29;124:981-991.
CAS Number
– 1158264-37-9
Molecular Weight
– 375.25
SMILES
– [H]Cl.[H]Cl.C1(CNC2=CC=C(C3=NC4=NC=CC=C4O3)C=C2)=NC=CC=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Enterovirus
Pathway
– Anti-infection
Product type
– Reference compound
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