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DBIBB
$175 – $1,440
Products Details
Product Description
– DBIBB is a specific nonlipid agonist of the type 2 G protein coupled receptor for lysophosphatidic acid (LPA2). DBIBB mitigates the gastrointestinal radiation syndrome, increases intestinal crypt survival and enterocyte proliferation, and reduces apoptosis. DBIBB represents a agent candidate capable of mitigating acute radiation syndrome caused by high-dose γ-radiation to the hematopoietic and gastrointestinal system[1].
Web ID
– HY-117779
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C23H20N2O6S
References
– [1]Patil R, et al. Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist. Chem Biol. 2015;22(2):206-216.
CAS Number
– 1569309-92-7
Molecular Weight
– 452.48
Compound Purity
– 99.07
SMILES
– O=C(N1CCCCNS(C2=C(C=CC=C2)C(O)=O)(=O)=O)C3=C4C(C=CC=C4C1=O)=CC=C3
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
