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DB-0646
$450 – $1,800
Products Details
Product Description
– DB-0646, a PROTAC, is a multi-kinase degrader[1].
Web ID
– HY-137343
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C52H51F3N14O7
References
– [1]Katherine A Donovan, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020 Dec 10;183(6):1714-1731.e10.
CAS Number
– 2769753-59-3
Molecular Weight
– 1041.05
Compound Purity
– 98.0
SMILES
– O=C(N1C2CCC(NC2=O)=O)C3=C(OCCCCCN4N=NC(CN5CCN(C6=NC=C(NC7=NC=C8C(N(C)C(N(C9=CC(NC(C%10=CC=CC(C(F)(F)F)=C%10)=O)=CC=C9C)C8)=O)=N7)C=C6)CC5)=C4)C=CC=C3C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– PROTACs
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
