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Dauricumine
$350 – $1,050
Products Details
Product Description
– Dauricumine is a chlorinated alkaloid that inhibits NF-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts[1][2].
Web ID
– HY-N11494
Shipping
– Room temperature
Molecular Formula
– C19H24ClNO6
References
– [1]Sugimoto Y, et, al. Chlorinated alkaloids in Menispermum dauricum DC: root culture. J Org Chem. 2001 May 18;66(10):3299-302.|[2]Lee JY, et, al. Anti-osteoclastogenic effects of isoquinoline alkaloids from the rhizome extract of Sinomenium acutum. Arch Pharm Res. 2016 May;39(5):713-20.
CAS Number
– 345641-00-1
Molecular Weight
– 397.85
SMILES
– COC([C@@]12[C@](C3)(CCN2C)[C@@]4([C@H](C1)Cl)[C@H](C(OC)=CC4=O)O)=C(OC)C3=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– NF-κB
Pathway
– NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
