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Dasotraline (hydrochloride)
$50 – $280
Products Details
Product Description
– Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.
Web ID
– HY-12850A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H16Cl3N
References
– [1]Guiard BP, et al. Characterization of the electrophysiological properties of triple reuptake inhibitors on monoaminergic neurons. Int J Neuropsychopharmacol. 2011 Mar;14(2):211-23.|[2]DeLorenzo C, et al. SEP-225289 serotonin and dopamine transporter occupancy: a PET study.
CAS Number
– 675126-08-6
Molecular Weight
– 328.66
Compound Purity
– 99.74
SMILES
– N[C@@H]1CC[C@@H](C2=CC=C(Cl)C(Cl)=C2)C3=CC=CC=C31.Cl[H]
Clinical Information
– Phase 3
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 31 mg/mL|H2O : 1.61 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Dopamine Transporter;Serotonin Transporter
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
