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Products Details
Product Description
– Dasotraline is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.
Web ID
– HY-12850
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H15Cl2N
References
– [1]Guiard BP, et al. Characterization of the electrophysiological properties of triple reuptake inhibitors on monoaminergic neurons. Int J Neuropsychopharmacol. 2011 Mar;14(2):211-23.
CAS Number
– 675126-05-3
Molecular Weight
– 292.20
SMILES
– N[C@@H]1CC[C@@H](C2=CC=C(Cl)C(Cl)=C2)C3=CC=CC=C31
Clinical Information
– Phase 3
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 31 mg/mL
Target
– Dopamine Transporter;Serotonin Transporter
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
